What Treatments Are Suitable Against Methamphetamine Abuse?
by Douglas Holmes on March 05, 2017

At this point in time, the most effective treatment for the addiction to methamphetamine is behavioral therapy like contingency management and cognitive-behavioral interventions. As an example of this, a 16-week approach to behavioral treatment referred to as the Matrix Model, which combines family education, behavioral therapy, 12-Step support, individual counseling, drug testing, and the encouragement to take up activities that are non-drug related, has proven to be an effective way to reduce methamphetamine abuse.


Contingency management interventions, whereby they provide incentives to continue with treatment and maintain abstinence, have also proven to be an efficient method. 


Further, an incentive-based method for the promotion of methamphetamine and cocaine abstinence known as Motivational Incentives for Enhancing Drug Abuse Recovery (MIEDAR), has likewise demonstrated good efficacy for those who abuse methamphetamine.


While medications have shown to be useful in the treatment of a variety of substance use disorders, currently there are no medications that are able to counteract the type of effects that methamphetamine demonstrates or that offer a prolonged level of abstinence or reduce methamphetamine abuse by those that are suffering from addiction to this drug.


Research into the development of medications that will treat addiction to different drugs, including stimulants, is now a priority for the National Institute on Drug Abuse (NIDA). 


Among these, one approach that is currently being trialed is the targeting of glial cells and their activity. A drug is known as AV411 (ibudilast) which suppresses the glial cells’ neuroinflammatory actions has demonstrated to inhibit the self-administration of methamphetamine in rats, and in clinical trials, this is being fast-tracked to determine its level of effectiveness and safety in humans that suffer from an addiction to methamphetamine. 


Some approaches are currently being studied in which the human body’s immune system is made capable of neutralizing the blood within the bloodstream prior to it reaching the brain. Such approaches include the injection into the user of vaccines or antimethamphetamine antibodies that have the capacity to stimulate the body, so it produces such antibodies in and of itself.


A clinical study has begun whereby researchers are aiming to ascertain the level of safety of an antimethamphetamine monoclonal antibody (referred to as mAb7F9) in those that are addicted to methamphetamine use.



Where can you Get More Information about Methamphetamine and is Help Available to Those that Abuse the Drug?


To find out more about methamphetamine as well as other drugs that are frequently misused, you can go to the NIDA website, or get in touch with the DrugPubs Research Dissemination Center. If help with methamphetamine dependence is required, get in contact with Florida Rehab. Florida Rehab employs a team of professionals that have many years of experience in dealing with people who suffer from methamphetamine abuse as well as other forms of drug and alcohol dependence.

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